A Facile Synthesis of Raltegravir Potassium—An HIV Integrase Inhibitor-Reference-Cited by-同舟云学术

A Facile Synthesis of Raltegravir Potassium—An HIV Integrase Inhibitor

Published:2019-08-14 Issue:9 Volume:56 Page:2683-2690
ISSN:0022-152X
Container-title:Journal of Heterocyclic Chemistry
language:en
Short-container-title:J. Heterocyclic Chem.

Author:

Karumanchi Kishore¹²^ORCID,Nangi Gangadhara Bhima Shankar¹,Danda Subba Reddy¹,Chavakula Ramadas¹,Korupolu Raghu Babu²,Bonige Kishore Babu²

Affiliation:

1. Chemical Research and DevelopmentAPL Research Centre‐II, Aurobindo Pharma Ltd. Survey No. 71 & 72, Indrakaran Village, Kandi Mandal Sangareddy Telangana 502329 India

2. Department of Engineering ChemistryAndhra University College of Engineering Visakhapatnam Andhra Pradesh 530003 India

Publisher

Wiley

Subject

Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jhet.3663

Reference12 articles.

1. Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

2. Crescenzi B.;Gardelli C.;Muragila E.;Orvieto F.;Pace P.;Pescatore G.;Petrocchi A.;Poma M.;Rowley M.;Scarpelli R.;Summa V.;Nizi E. USPatent 7 169 780 B2 2001; Chem Abstr 138:354001.

3. Development of a Second-Generation, Highly Efficient Manufacturing Route for the HIV Integrase Inhibitor Raltegravir Potassium

4. Identification, Synthesis, and Strategy For Minimization of Potential Impurities Observed In Raltegravir Potassium Drug Substance

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