Predictive Performance of Physiologically Based Pharmacokinetic Models for the Effect of Food on Oral Drug Absorption: Current Status-Reference-Cited by-同舟云学术

Predictive Performance of Physiologically Based Pharmacokinetic Models for the Effect of Food on Oral Drug Absorption: Current Status

Published:2017-11-23 Issue:2 Volume:7 Page:82-89
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacometrics Syst. Pharmacol.

Author:

Li Mengyao¹²,Zhao Ping¹³,Pan Yuzhuo⁴,Wagner Christian¹⁵

Affiliation:

1. Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, United States Food and Drug Administration; Silver Spring Maryland USA

2. Merck & Co, Inc, Kennilworth; New Jersey USA

3. Bill & Melinda Gates Foundation; Seattle Washington USA

4. Office of Generic Drugs, Center for Drug Evaluation and Research, United States Food and Drug Administration; Silver Spring Maryland USA

5. Current affiliation: Merck KGaA; Darmstadt Germany

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Reference37 articles.

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2. Incorporation of the time-varying postprandial increase in splanchnic blood flow into a PBPK model to predict the effect of food on the pharmacokinetics of orally administered high-extraction drugs;Rose;AAPS J.,2017

3. Current methods for predicting human food effect;Lentz;AAPS J.,2008

4. https://www.fda.gov/downloads/drugs/guidances/ucm377465.pdf 2013

5. Drug, meal and formulation interactions influencing drug absorption after oral administration. Clinical implications;Fleisher;Clin. Pharmacokinet.,1999

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