A comparison of subgroup identification methods in clinical drug development: Simulation study and regulatory considerations
Author:
Affiliation:
1. Department of Medical StatisticsUniversity Medical Center Göttingen Göttingen Germany
2. Federal Institute for Drugs and Medical Devices (BfArM) Research Department Bonn Germany
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology,Statistics and Probability
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/pst.1951
Reference49 articles.
1. HuberC FriedeT StinglJ BendaN.Classification of biomarkers to be used as companion diagnosticy: consequences for regulatory decisions on biomarker driven patient selection.2018. Manuscript in preparation.
2. Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
3. Wild-TypeKRASIs Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
4. Clinical Trial Designs for Predictive Biomarker Validation: Theoretical Considerations and Practical Challenges
5. KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab
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