Comparing algorithms for characterizing treatment effect heterogeneity in randomized trials

Author:

Sun Sophie1,Sechidis Konstantinos2,Chen Yao1,Lu Jiarui1,Ma Chong3,Mirshani Ardalan1,Ohlssen David1,Vandemeulebroecke Marc4,Bornkamp Björn2ORCID

Affiliation:

1. Advanced Methodology and Data Science Novartis Pharmaceuticals Corporation East Hanover New Jersey USA

2. Advanced Methodology and Data Science Novartis Pharma AG Basel Switzerland

3. Early Development Analytics Novartis Pharmaceuticals Corporation Cambridge Massachusetts USA

4. Clinical Development and Analytics Novartis Pharma AG Basel Switzerland

Publisher

Wiley

Subject

Statistics, Probability and Uncertainty,General Medicine,Statistics and Probability

Reference75 articles.

1. A comparative study of subgroup identification methods for differential treatment effect: Performance metrics and recommendations;Alemayehu D.;Statistical Methods in Medical Research,2018

2. Tutorial on statistical considerations on subgroup analysis in confirmatory clinical trials;Alosh M.;Statistics in Medicine,2017

3. Recursive partitioning for heterogeneous causal effects;Athey S.;Proceedings of the National Academy of Sciences,2016

4. Generalized random forests;Athey S.;The Annals of Statistics,2019

5. Estimating treatment effects with causal forests: An application;Athey S.;Observational Studies,2019

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