The interplay of protein engineering and glycoengineering to fine‐tune antibody glycosylation and its impact on effector functions-Reference-Cited by-同舟云学术

The interplay of protein engineering and glycoengineering to fine‐tune antibody glycosylation and its impact on effector functions

Published:2021-10-20 Issue:1 Volume:119 Page:102-117
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnol Bioeng

Author:

Wang Qiong¹^ORCID,Wang Tiexin¹,Zhang Roushu²,Yang Shuang³^ORCID,McFarland Kevin S.¹^ORCID,Chung Cheng‐Yu¹^ORCID,Jia Hongpeng⁴,Wang Lai‐Xi²^ORCID,Cipollo John F.³,Betenbaugh Michael J.¹^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering Johns Hopkins University Baltimore Maryland USA

2. Department of Chemistry and Biochemistry University of Maryland College Park Maryland USA

3. Division of Bacterial, Parasitic and Allergenic Products (DBPAP), Laboratory for Bacterial Polysaccharides, Center for Biologics Evaluation and Research US Food and Drug Administration Silver Spring Maryland USA

4. Division of Pediatric Surgery, Department of Surgery Johns Hopkins University Baltimore Maryland USA

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.27953

Reference73 articles.

1. Intravenous immunoglobulin and thymoglobulin facilitate kidney transplantation in complement-dependent cytotoxicity B-cell and flow cytometry T- or B-cell crossmatch-positive patients

2. Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies

3. The effect of the removal of sialic acid, galactose and total carbohydrate on the functional activity of Campath-1H

4. Integrated Genome and Protein Editing Swaps α ‐2,6 Sialylation for α ‐2,3 Sialic Acid on Recombinant Antibodies from CHO

5. Combinatorial genome and protein engineering yields monoclonal antibodies with hypergalactosylation from CHO cells

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