Discovery of Imidazoquinazolinone Derivatives as TSPO Ligands Modulating Neurosteroidogenesis and Cellular Bioenergetics in Neuroblastoma Cells Expressing Amyloid Precursor Protein-Reference-Cited by-同舟云学术

Discovery of Imidazoquinazolinone Derivatives as TSPO Ligands Modulating Neurosteroidogenesis and Cellular Bioenergetics in Neuroblastoma Cells Expressing Amyloid Precursor Protein

Published:2017-07-31 Issue:22 Volume:2 Page:6452-6457
ISSN:2365-6549
Container-title:ChemistrySelect
language:en
Short-container-title:ChemistrySelect

Author:

Hallé François¹,Lejri Imane²³⁴,Abarghaz Mustapha¹,Grimm Amandine²³,Klein Christian⁴,Maitre Michel⁴,Schmitt Martine¹,Bourguignon Jean-Jacques¹,Mensah-Nyagan Ayikoe Guy⁴,Eckert Anne²³,Bihel Frederic¹

Affiliation:

1. Laboratoire d'Innovation Thérapeutique, UMR7200, CNRS; Université de Strasbourg; Faculté de pharmacie; 74, route du Rhin 67400 Illkirch France

2. Neurobiology Laboratory for Brain Aging and Mental Health; Transfaculty Research Platform, Molecular & Cognitive Neuroscience; University of Basel; Wilhelm Klein-Str. 27, CH- 4012 Basel Switzerland

3. Psychiatric University Clinics; University of Basel; Wilhelm Klein-Str. 27, CH- 4012 Basel Switzerland

4. Biopathologie de la Myéline; Neuroprotection et Stratégies Thérapeutiques, INSERM U1119; Fédération de Médecine Translationnelle de Strasbourg (FMTS); Université de Strasbourg; 11 rue Humann 67 000 Strasbourg France

Publisher

Wiley

Subject

General Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/slct.201701565/fullpdf

Reference23 articles.

1. A Direct Interaction Between Mitochondrial Proteins and Amyloid-β Peptide and its Significance for the Progression and Treatment of Alzheimer’s Disease

2. Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity

3. Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer’s Disease

4. Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

5. Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

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4. Mitochondria as a promising target for developing novel agents for treating Alzheimer's disease;Medicinal Research Reviews;2020-07-20

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