Transition Metal‐free gem ‐difluorocyclopropanation of Alkenes with CF 3 SiMe 3 −NaI System: a Recipe for Electron‐deficient Substrates-Reference-Cited by-同舟云学术

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Transition Metal‐free gem ‐difluorocyclopropanation of Alkenes with CF 3 SiMe 3 −NaI System: a Recipe for Electron‐deficient Substrates

Published:2018-09-26 Issue:21 Volume:360 Page:4104-4114
ISSN:1615-4150
Container-title:Advanced Synthesis & Catalysis
language:en
Short-container-title:Adv. Synth. Catal.

Author:

Nosik Pavel S.¹²,Ryabukhin Sergey V.²,Grygorenko Oleksandr O.¹²,Volochnyuk Dmitriy M.³

Affiliation:

1. Enamine Ltd. Chervonotkatska Street 78 Kyiv 02094 Ukraine

2. National Taras Shevchenko University of Kyiv Volodymyrska Street 64 Kyiv 01601 Ukraine

3. Institute of Organic ChemistryNational Academy of Sciences of Ukraine Murmanska Street 5 Kyiv 02094 Ukraine

Funder

Enamine Ltd

Publisher

Wiley

Subject

General Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/adsc.201801006

Reference35 articles.

1. Fluorine in Medicinal Chemistry

2. Applications of Fluorine in Medicinal Chemistry

3. Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

4. Fluorination methods in drug discovery

5. Fluorinated Pharmaceuticals: Advances in Medicinal Chemistry

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1. Fluorinated building blocks in drug design: new pathways and targets;Future Medicinal Chemistry;2024-07-17

2. TMSCF₃-Mediated Conversion of Salicylates into α,α-Difluoro-3-coumaranones: Chain Kinetics, Anion-Speciation, and Mechanism;The Journal of Organic Chemistry;2023-12-02

3. 6,6-Difluorobicyclo[3.1.0]hexane as a rigidified 4,4-difluorocyclohexane mimetic: Multigram synthesis, physicochemical characterization, and incorporation into Maraviroc analogs;Journal of Fluorine Chemistry;2023-11

4. Recent Advances in Monofluorinated Carbenes, Carbenoids, Ylides, and Related Species;Chemistry – A European Journal;2023-10-30

5. Synthesis of Selectively gem‐Difluorinated Molecules; Chiral gem‐Difluorocyclopropanes via Chemo‐Enzymatic Reaction and gem‐Difluorinated Compounds via Radical Reaction;The Chemical Record;2023-03-22

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