1. School of Pharmaceutical SciencesZhengzhou University Zhengzhou 450001 People's Republic of China E-mail: zzuyubin.weebly.com
2. Co-Innovation Center of Henan Province for New Drug R & D and Preclinical Safety Zhengzhou 450001 People's Republic of China
3. Key Laboratory of Advanced Technology of Drug Preparation Technologies (Zhengzhou University)Ministry of Education of China Zhengzhou 450001 People's Republic of China
4. State key Laboratory of Pharmaceutical BiotechnologyNanjing University Nanjing 210023, Jiangsu People's Republic of China