Genetic Dissection of Acute Anterior Uveitis Reveals Similarities and Differences in Associations Observed With Ankylosing Spondylitis

Author:

Robinson Philip C.1,Claushuis Theodora A. M.1,Cortes Adrian1,Martin Tammy M.2,Evans David M.1,Leo Paul1,Mukhopadhyay Pamela1,Bradbury Linda A.1,Cremin Katie1,Harris Jessica1,Maksymowych Walter P.3,Inman Robert D.4,Rahman Proton5,Haroon Nigil4,Gensler Lianne6,Powell Joseph E.7,van der Horst-Bruinsma Irene E.8,Hewitt Alex W.9,Craig Jamie E.10,Lim Lyndell L.9,Wakefield Denis11,McCluskey Peter12,Voigt Valentina13,Fleming Peter13,Degli-Esposti Mariapia14,Pointon Jennifer J.15,Weisman Michael H.16,Wordsworth B. Paul15,Reveille John D.17,Rosenbaum James T.18,Brown Matthew A.1,

Affiliation:

1. University of Queensland Diamantina Institute, Translational Research Institute and Princess Alexandra Hospital, Woolloongabba; Brisbane Queensland Australia

2. Casey Eye Institute, Oregon Health & Science University; Portland

3. University of Alberta, Edmonton; Alberta Canada

4. University of Toronto, Toronto; Ontario Canada

5. Memorial University, St. John's; Newfoundland Canada

6. University of California; San Francisco

7. Queensland Brain Institute University of Queensland, Brisbane; Queensland Australia

8. VU University Medical Centre; Amsterdam The Netherlands

9. Centre for Eye Research Australia, University of Melbourne and Royal Victorian Eye and Ear Hospital, Melbourne; Victoria Australia

10. Flinders Medical Centre and Flinders University, Adelaide; South Australia Australia

11. School of Medical Science, University of New South Wales, Sydney; New South Wales Australia

12. University of Sydney, Sydney; New South Wales Australia

13. Lions Eye Institute, Nedlands; Western Australia Australia

14. Lions Eye Institute, Nedlands, Western Australia, Australia, and University of Western Australia, Crawley; Western Australia Australia

15. NIHR Oxford Comprehensive Biomedical Research Centre, and NIHR Oxford Musculoskeletal Biomedical Research Unit, and Nuffield Orthopaedic Centre, Headington; Oxford UK

16. Cedars-Sinai Medical Center and University of California at Los Angeles David Geffen School of Medicine; Los Angeles California

17. University of Texas Health Science Center at Houston

18. Casey Eye Institute, Oregon Health & Science University, and Legacy Devers Eye Clinic; Portland Oregon

Funder

National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Health and Medical Research Council

Publisher

Wiley

Subject

Immunology,Rheumatology,Immunology and Allergy

Reference51 articles.

1. The lifetime cumulative incidence of acute anterior uveitis in a normal population and its relation to ankylosing spondylitis and histocompatibility antigen HLA-B27;Linssen;Invest Ophthalmol Vis Sci,1991

2. Understanding autoimmune uveitis through animal models: the Friedenwald lecture;Caspi;Invest Ophthalmol Vis Sci,2011

3. Incidence and prevalence of uveitis in Northern California: the Northern California Epidemiology of Uveitis Study;Gritz;Ophthalmology,2004

4. Genetic control of susceptibility in clinical and experimental uveitis;Pennesi;Int Rev Immunol,2002

5. A familial study of the inheritance of HLA-B27-positive acute anterior uveitis;Derhaag;Am J Ophthalmol,1988

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