Commentary on “The Universally Unrecognized Assumption in Predicting Drug Clearance and Organ Extraction Ratio”
Author:
Affiliation:
1. Centre for Applied Pharmacokinetic Research, Manchester School of Pharmacy; University of Manchester; Manchester UK
2. Leslie Dan Faculty of Pharmacy; University of Toronto; Toronto ON Canada
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpt.921/fullpdf
Reference11 articles.
1. The universally unrecognized assumption in predicting drug clearance and organ extraction ratio;Benet;Clin. Pharmacol. Ther.
2. Clearance concepts in pharmacokinetics;Rowland;J. Pharmacokinet. Biopharm.,1973
3. Influence of route of administration on drug availability;Rowland;J. Pharm. Sci.,1972
4. Autoradiographic evidence for hepatic lobular concentration gradient of bile acid derivative;Jones;Am. J. Physiol.,1980
5. Hepatic clearance of drugs. II. Experimental evidence for acceptance of the “well-stirred” model over the “parallel tube” model using lidocaine in the perfused rat liver in situ preparation;Pang;J. Pharmacokin. Biopharm.,1977
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