Fragment-Based Drug Design Facilitated by Protein-Templated Click Chemistry: Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin-Reference-Cited by-同舟云学术

Fragment-Based Drug Design Facilitated by Protein-Templated Click Chemistry: Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin

Published:2016-09-07 Issue:42 Volume:22 Page:14826-14830
ISSN:0947-6539
Container-title:Chemistry - A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Mondal Milon¹^ORCID,Unver M. Yagiz¹^ORCID,Pal Asish²,Bakker Matthijs¹,Berrier Stephan P.¹,Hirsch Anna K. H.¹^ORCID

Affiliation:

1. Stratingh Institute for Chemistry; University of Groningen; Nijenborgh 7 9747 AG Groningen The Netherlands

2. Institute of Nano Science and Technology; Sector 64; Mohali, Punjab 160062 India

Funder

Netherlands Organisation for Scientific Research

Dutch Ministry of Education, Culture, Science

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Reference52 articles.

1. Fragment-Based Drug Discovery

2. A decade of fragment-based drug design: strategic advances and lessons learned

3. Evolutions in fragment-based drug design: the deconstruction–reconstruction approach

4. Discovering High-Affinity Ligands for Proteins: SAR by NMR

5. Introduction to Fragment-Based Drug Discovery

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Biocompatible reactions: advances in kinetic target-guided synthesis;Trends in Chemistry;2023-09

2. Linkers in fragment-based drug design: an overview of the literature;Expert Opinion on Drug Discovery;2023-07-19

3. Development of potent inhibitors by fragment‐linking strategies;Chemical Biology & Drug Design;2022-08-16

4. 2.5 CuAAC and Metal-Free 1,3-Dipolar Huisgen Cycloadditions in Drug Discovery;Click Chemistry;2022

5. Identification of isoform/domain-selective fragments from the selection of DNA-encoded dynamic library;Bioorganic & Medicinal Chemistry;2021-09