Synthesis and Demonstration of the Biological Relevance of sp3 -rich Scaffolds Distantly Related to Natural Product Frameworks-Reference-Cited by-同舟云学术

Synthesis and Demonstration of the Biological Relevance of sp3 -rich Scaffolds Distantly Related to Natural Product Frameworks

Published:2017-10-06 Issue:60 Volume:23 Page:15227-15232
ISSN:0947-6539
Container-title:Chemistry - A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Foley Daniel J.¹²^ORCID,Craven Philip G. E.¹²^ORCID,Collins Patrick M.³,Doveston Richard G.¹²^ORCID,Aimon Anthony¹²,Talon Romain⁴,Churcher Ian⁵,von Delft Frank³⁴^ORCID,Marsden Stephen P.²^ORCID,Nelson Adam¹²^ORCID

Affiliation:

1. Astbury Centre for Structural Molecular Biology; University of Leeds; Leeds LS2 9JT UK

2. School of Chemistry; University of Leeds; Leeds LS2 9JT UK

3. Diamond Light Source Ltd; Harwell Science and Innovation Campus; Didcot OX11 0QX UK

4. Structural Genomics Consortium, Nuffield Department of Medicine; University of Oxford, Roosevelt Drive; Oxford OX3 7DQ UK

5. GlaxoSmithKline Medicines Research Centre; Stevenage SG1 2NY UK,BenevolentBio, Churchway London NW1 1LW UK

Funder

Engineering and Physical Sciences Research Council

Engineering and Physical Sciences Research Council (GB)

FP7 International Cooperation

Wellcome Trust

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Reference71 articles.

1. Structural Diversity of Organic Chemistry. A Scaffold Analysis of the CAS Registry

2. What Do Medicinal Chemists Actually Make? A 50-Year Retrospective

3. The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

4. Factors Determining the Selection of Organic Reactions by Medicinal Chemists and the Use of These Reactions in Arrays (Small Focused Libraries)

Cited by 51 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Cooperative Phosphine-Photoredox Catalysis Enables N–H Activation of Azoles for Intermolecular Olefin Hydroamination;Journal of the American Chemical Society;2024-07-10

2. Construction of the Akuammiline Alkaloid Core Structure via Stereoselective E-Ring Formation;The Journal of Organic Chemistry;2024-07-02

3. Engaging Alkenes in Metallaphotoredox: A Triple Catalytic, Radical Sorting Approach to Olefin-Alcohol Cross-Coupling;Journal of the American Chemical Society;2024-04-24

4. Net Intermolecular Silyloxypyrone-Based (5+2) Cycloadditions Utilizing Amides as Enabling and Cleavable Tethers;Organic Letters;2023-09-26

5. Fragtory: Pharmacophore-Focused Design, Synthesis, and Evaluation of an sp³-Enriched Fragment Library;Journal of Medicinal Chemistry;2023-05-02