Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase-Reference-Cited by-同舟云学术

Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase

Published:2020-01-20 Issue:3 Volume:29 Page:779-788
ISSN:0961-8368
Container-title:Protein Science
language:en
Short-container-title:Protein Science

Author:

Michalska Karolina¹²,Chang Changsoo¹²,Maltseva Natalia I.¹²,Jedrzejczak Robert¹²,Robertson Gregory T.³,Gusovsky Fabian⁴,McCarren Patrick⁵,Schreiber Stuart L.⁵,Nag Partha P.⁵,Joachimiak Andrzej¹²⁶^ORCID

Affiliation:

1. Center for Structural Genomics of Infectious Diseases, Consortium for Advanced Science and Engineering University of Chicago Chicago Illinois

2. Structural Biology Center, X‐ray Science Division Argonne National Laboratory Argonne Illinois

3. Colorado State University Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology Fort Collins Colorado

4. Eisai Co, Ltd. World Health Initiative Andover Massachusetts

5. Broad Institute of MIT and Harvard Cambridge Massachusetts

6. Department of Biochemistry and Molecular Biology University of Chicago Chicago Illinois

Funder

Biological and Environmental Research

National Institutes of Health

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/pro.3825

Reference42 articles.

1. WHO W. H. O. Global tuberculosis report2019. 120 (World Health Organization https://www.who.int/tb/global-report-2019 2019).

2. Enzyme targets for drug design of new anti-virulence therapeutics

3. Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing

4. A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase

5. Indoleamine 2,3-Dioxygenase 1 Is a Lung-Specific Innate Immune Defense Mechanism That Inhibits Growth of Francisella tularensis Tryptophan Auxotrophs

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