A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase-Reference-Cited by-同舟云学术

A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase

Published:2017-07-03 Issue:9 Volume:13 Page:943-950
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Wellington Samantha,Nag Partha P,Michalska Karolina,Johnston Stephen E,Jedrzejczak Robert P,Kaushik Virendar K,Clatworthy Anne E,Siddiqi Noman,McCarren Patrick,Bajrami Besnik,Maltseva Natalia I,Combs Senya,Fisher Stewart L,Joachimiak Andrzej,Schreiber Stuart L,Hung Deborah T

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.2420.pdf

Reference60 articles.

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2. Zumla, A., Nahid, P. & Cole, S.T. Advances in the development of new tuberculosis drugs and treatment regimens. Nat. Rev. Drug Discov. 12, 388–404 (2013).

3. Mdluli, K., Kaneko, T. & Upton, A. The tuberculosis drug discovery and development pipeline and emerging drug targets. Cold Spring Harb. Perspect. Med. 5, a021154 (2015).

4. Katsuno, K. et al. Hit and lead criteria in drug discovery for infectious diseases of the developing world. Nat. Rev. Drug Discov. 14, 751–758 (2015).

5. Andries, K. et al. A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis. Science 307, 223–227 (2005).

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