Key Learnings from Performance of the U.S. EPA Endocrine Disruptor Screening Program (EDSP) Tier 1 In Vitro Assays

Author:

LeBaron Matthew J.1,Coady Katie K.1,O'Connor John C.2,Nabb Diane L.2,Markell Lauren K.2,Snajdr Suzanne2,Sue Marty M.1

Affiliation:

1. Toxicology & Environmental Research and Consulting The Dow Chemical Company Midland Michigan

2. DuPont Haskell Global Centers for Health and Environmental Sciences Newark Delaware

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Developmental Biology,Toxicology,Embryology

Reference32 articles.

1. Understanding nuclear receptors using computational methods

2. Selective Retention of Dihydrotestosterone by Prostatic Nuclei

3. The intranuclear binding of testosterone and 5‐alpha‐androstan‐17‐beta‐ol‐3‐one by rat prostate;Bruchovsky N;J Biol Chem,1968

4. Estrogen receptors: An evaluation of cytoplasmic-nuclear interactions in a cell-free system and a method for assay

5. EDSTAC.1998.Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC) final report. Available at:http://www.epa.gov/scipoly/oscpendo/pubs/edspoverview/finalrpt.htm. Accessed January 28 2014.

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