Low concentrations of cadmium chloride promotes protein translation and improve cell line productivity
Author:
Affiliation:
1. Institute for Drug ResearchThe School of PharmacyThe Hebrew University of JerusalemJerusalem Israel
2. Molecular Biology and Fermentation Unit, Valin TechnologiesYavne Israel
3. Biotherapeutics Unit, Celgene CorporationSan Diego California
Funder
Israel Science Foundation
Publisher
Wiley
Subject
Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.26888
Reference31 articles.
1. mTORC1 signaling and the metabolic control of cell growth
2. Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death
3. Multiplex Genome Engineering Using CRISPR/Cas Systems
4. Understanding translational control mechanisms of the mTOR pathway in CHO cells by polysome profiling
5. Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton
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3. Towards Enhancing Therapeutic Glycoprotein Bioproduction: Interventions in the PI3K/AKT/mTOR Pathway;Cell Structure and Function;2019
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