Single‐Cell Transcriptomic Census of Endothelial Changes Induced by Matrix Stiffness and the Association with Atherosclerosis-Reference-Cited by-同舟云学术

Single‐Cell Transcriptomic Census of Endothelial Changes Induced by Matrix Stiffness and the Association with Atherosclerosis

Published:2022-09-12 Issue:47 Volume:32 Page:2203069
ISSN:1616-301X
Container-title:Advanced Functional Materials
language:en
Short-container-title:Adv Funct Materials

Author:

Zamani Maedeh¹²,Cheng Yu‐Hao³⁴,Charbonier Frank⁵,Gupta Vivek Kumar⁵,Mayer Aaron T.⁶,Trevino Alexandro E.⁶,Quertermous Thomas⁷,Chaudhuri Ovijit⁵,Cahan Patrick³⁴⁸,Huang Ngan F.¹²⁹¹⁰^ORCID

Affiliation:

1. Department of Cardiothoracic Surgery Stanford University Stanford CA 94305 USA

2. Stanford Cardiovascular Institute Stanford University Stanford CA 94305 USA

3. Department of Molecular Biology and Genetics Johns Hopkins University School of Medicine Baltimore MD 21205 USA

4. Institute for Cell Engineering Johns Hopkins University School of Medicine Baltimore MD 21205 USA

5. Department of Mechanical Engineering Stanford University Stanford CA 94305 USA

6. Enable Medicine, Inc Menlo Park 94025 USA

7. Division of Cardiovascular Medicine Stanford School of Medicine Stanford CA 94305 USA

8. Department of Biomedical Engineering Johns Hopkins University School of Medicine Baltimore MD 21205 USA

9. Department of Chemical Engineering Stanford University Stanford CA 94305 USA

10. Veterans Affairs Palo Alto Health Care System Palo Alto CA 94304 USA

Funder

National Institutes of Health

U.S. Department of Veterans Affairs

American Heart Association

National Science Foundation

National Heart, Lung, and Blood Institute

Publisher

Wiley

Subject

Electrochemistry,Condensed Matter Physics,Biomaterials,Electronic, Optical and Magnetic Materials

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/adfm.202203069

Reference50 articles.

1. Endothelial-to-mesenchymal transition drives atherosclerosis progression

2. TGF-β Signaling Mediates Endothelial-to-Mesenchymal Transition (EndMT) During Vein Graft Remodeling

3. Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

4. Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction

5. Endothelial-to-mesenchymal transition: Pathogenesis and therapeutic targets for chronic pulmonary and vascular diseases

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