Assessment of multiple cytochrome P450 activities in metabolically inactivated human liver microsomes and roles of P450 2C isoforms in reaction phenotyping studies-Reference-Cited by-同舟云学术

Assessment of multiple cytochrome P450 activities in metabolically inactivated human liver microsomes and roles of P450 2C isoforms in reaction phenotyping studies

Published:2017-12-21 Issue:2 Volume:39 Page:116-121
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm Drug Dispos

Author:

Murayama Norie¹,Yajima Kanako¹²,Hikawa Mikiko¹,Shimura Kanami¹,Ishii Yu¹,Takada Masaki¹,Uno Yasuhiro²,Utoh Masahiro¹²,Iwasaki Kazuhide²,Yamazaki Hiroshi¹^ORCID

Affiliation:

1. Laboratory of Drug Metabolism and Pharmacokinetics; Showa Pharmaceutical University; Machida Tokyo 194-8543 Japan

2. Pharmacokinetics and Bioanalysis Center; Shin Nippon Biomedical Laboratories, Ltd; Kainan Wakayama Japan

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference15 articles.

1. Prediction of in vivo drug-drug interactions from in vitro data: impact of incorporating parallel pathways of drug elimination and inhibitor absorption rate constant;Brown;British Journal of Clinical Pharmacology,2005

2. Prediction of the effects of genetic polymorphism on the pharmacokinetics of CYP2C9 substrates from in vitro data;Kusama;Pharmaceutical Research,2009

3. Improvement of the chemical inhibition phenotyping assay by cross-reactivity correction;Njuguna;Drug Metabolism and Personalized Therapy,2016

4. Mechanism-based inactivation of human cytochrome p450 enzymes and the prediction of drug-drug interactions;Obach;Drug Metabolism & Disposition,2007

5. Drug interactions of diclofenac and its oxidative metabolite with human liver microsomal cytochrome P450 1A2-dependent drug oxidation;Ohyama;Xenobiotica,2014

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