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Clinical Importance of Monitoring Unbound Valproic Acid Concentration in Patients with Hypoalbuminemia

  • Published:2017-07-18 Issue:8 Volume:37 Page:900-907
  • ISSN:0277-0008
  • Container-title:Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
  • language:en
  • Short-container-title:Pharmacotherapy

Author:

Doré Maxime1,San Juan Adriana E.2,Frenette Anne Julie134,Williamson David134

Affiliation:

1. Department of Pharmacy; Hôpital du Sacré-Coeur de Montréal; Montreal Québec Canada

2. Department of Pharmacy; Complejo Hospitalario de Navarra; Pamplona Spain

3. Research Center; Hôpital du Sacré-Coeur de Montréal; Montreal Québec Canada

4. Faculty of Pharmacy; University of Montreal; Montreal Québec Canada

Funder

Fonds de Recherche du Québec - Santé

Publisher

Wiley

Subject

Pharmacology (medical)

Reference26 articles.

1. Valproic acid pathway: pharmacokinetics and pharmacodynamics;Ghodke-Puranik;Pharmacogenet Genomics,2013

2. Valproic acid poisoning: an evidence-based consensus guideline for out-of-hospital management;Manoguerra;Clin Toxicol,2008

3. Abbott Laboratories Limited Canadian product monograph of Epival 2015

4. Free drug metabolic clearance in elderly people;Butler;Clin Pharmacokinet,2008

5. Elevated free fractions of valproic acid in a heart transplant patient with hypoalbuminemia;Haroldson;Ann Pharmacother,2000

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