Synthesis, analytical characterization, and monoamine transporter activity of the new psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation from its ortho - and meta - positional isomers-Reference-Cited by-同舟云学术

Synthesis, analytical characterization, and monoamine transporter activity of the new psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation from its ortho - and meta - positional isomers

Published:2018-05-23 Issue:9 Volume:10 Page:1404-1416
ISSN:1942-7603
Container-title:Drug Testing and Analysis
language:en
Short-container-title:Drug Test Anal

Author:

McLaughlin Gavin¹²^ORCID,Baumann Michael H.³,Kavanagh Pierce V.¹,Morris Noreen⁴,Power John D.¹²^ORCID,Dowling Geraldine¹⁵,Twamley Brendan⁶,O'Brien John⁶,Hessman Gary⁶^ORCID,Westphal Folker⁷,Walther Donna³,Brandt Simon D.⁸^ORCID

Affiliation:

1. Department of Pharmacology and Therapeutics, School of Medicine, Trinity Centre for Health Sciences; St James's Hospital; Dublin Ireland

2. Forensic Science Ireland; Garda Headquarters; Dublin Ireland

3. Designer Drug Research Unit, Intramural Research Program; National Institute on Drug Abuse, National Institutes of Health; Baltimore Maryland

4. Department of Life & Physical Sciences; Faculty of Science and Health, Athlone Institute of Technology, Co.; Westmeath Ireland

5. Department of Life Sciences, School of Science; Sligo Institute of Technology; Ireland

6. School of Chemistry; Trinity College Dublin; Ireland

7. State Bureau of Criminal Investigation Schleswig-Holstein; Section Narcotics/Toxicology; Kiel Germany

8. School of Pharmacy and Biomolecular Sciences; Liverpool John Moores University; UK

Publisher

Wiley

Subject

Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/dta.2396/fullpdf

Reference37 articles.

1. Blough BE Rothman R Landavazo A Page KM Decker AM Preparation of phenylmorpholines and analogs thereof 2011

2. Medical Toxicology of Drug Abuse

3. Interaction of the anorectic medication, phendimetrazine, and its metabolites with monoamine transporters in rat brain;Rothman;Eur J Pharmacol,2002

4. GLC determination of phedimetrazine in human plasma, serum, or urine;Rudolph;J Pharm Sci,1983

5. A note on the identification of N-hydroxyphenmetrazine as a metabolic product of phendimetrazine and phenmetrazine;Beckett;J Pharm Pharmacol,1972

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