Unlocking the Anticancer Potential of Ionic Liquids

Author:

Mohd Noor Najihah1ORCID,Elgharbawy Amal A. M.2ORCID,Moniruzzaman Muhammad3ORCID,Goto Masahiro4ORCID

Affiliation:

1. International Islamic University Malaysia Department of Chemical Engineering and Sustainability, Kulliyyah of Engineering P.O. Box 10 50728 Kuala Lumpur Malaysia

2. International Islamic University Malaysia International Institute for Halal Research and Training (INHART) P.O. Box 10 50728 Kuala Lumpur Malaysia

3. Universiti Teknologi PETRONAS Chemical Engineering Department 32610 Seri Iskandar Perak Malaysia

4. Kyushu University Department of Applied Chemistry, Graduate School of Engineering 744 Motooka, Nishi-ku 819-0395 Fukuoka Japan

Abstract

AbstractDespite advances in cancer treatment, many types of cancer still have high mortality rates, and the existing therapies can cause considerable side effects. Therefore, discovering new therapies, especially ones with fewer side effects, is desirable to improve the outcomes for cancer patients. Ionic liquids (ILs) have emerged as potential candidates for cancer treatment because of their particular physicochemical properties, which can be tailored for specific applications. In recent years, interest in exploring the potential of ILs in cancer treatment has been growing, and several studies have demonstrated the effectiveness of ILs in inhibiting cancer‐cell growth. This review provides insight into the anticancer potential of ILs, exploring the diverse applications and the underlying mechanisms behind the cytotoxicity toward cancer cells of ILs. Understanding the mechanisms behind the cytotoxicity of ILs can aid in the design and optimization of IL‐based cancer therapies. By focusing on specific pathways and targets, IL‐based cancer therapies may be developed that offer new possibilities for treating this devastating disease.

Funder

Ministry of Higher Education, Malaysia

Publisher

Wiley

Subject

Industrial and Manufacturing Engineering,Filtration and Separation,Process Chemistry and Technology,Biochemistry,Chemical Engineering (miscellaneous),Bioengineering

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