Evidence for a Common Non-Heme Chelatable-Iron-Dependent Activation Mechanism for Semisynthetic and Synthetic Endoperoxide Antimalarial Drugs-Reference-Cited by-同舟云学术

Evidence for a Common Non-Heme Chelatable-Iron-Dependent Activation Mechanism for Semisynthetic and Synthetic Endoperoxide Antimalarial Drugs

Published:2007-08-20 Issue:33 Volume:119 Page:6394-6399
ISSN:0044-8249
Container-title:Angewandte Chemie
language:de
Short-container-title:Angew. Chem.

Author:

Stocks Paul A.,Bray Patrick G.,Barton Victoria E.,Al-Helal Mohammed,Jones Michael,Araujo Nuna C.,Gibbons Peter,Ward Stephen A.,Hughes Ruth H.,Biagini Giancarlo A.,Davies Jill,Amewu Richard,Mercer Amy E.,Ellis Gemma,O'Neill Paul M.

Publisher

Wiley

Subject

General Medicine

Reference52 articles.

1. A Medicinal Chemistry Perspective on Artemisinin and Related Endoperoxides

2. From Artemisinin to New Artemisinin Antimalarials: Biosynthesis, Extraction, Old and New Derivatives, Stereochemistry and Medicinal Chemistry Requirements

3. Knowledge of the Proposed Chemical Mechanism of Action and Cytochrome P450 Metabolism of Antimalarial Trioxanes Like Artemisinin Allows Rational Design of New Antimalarial Peroxides

4. Synthetic peroxides as antimalarials

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