Synthesis of 6-Azaspiro[4.3]alkanes: Innovative Scaffolds for Drug Discovery-Reference-Cited by-同舟云学术

Synthesis of 6-Azaspiro[4.3]alkanes: Innovative Scaffolds for Drug Discovery

Published:2017-07-05 Issue:31 Volume:2017 Page:4530-4542
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur. J. Org. Chem.

Author:

Chalyk Bohdan A.¹,Isakov Andrei A.¹²,Butko Maryna V.¹³,Hrebeniuk Kateryna V.¹,Savych Olena V.¹²,Kucher Olexandr V.¹⁴,Gavrilenko Konstantin S.¹⁵,Druzhenko Tetiana V.¹⁶,Yarmolchuk Vladimir S.¹⁶,Zozulya Sergey¹⁵,Mykhailiuk Pavel K.²^ORCID

Affiliation:

1. Enamine Ltd.; Chervonotkatska 78 02094 Kyiv Ukraine

2. Department of Chemistry; Taras Shevchenko National University of Kyiv; Volodymyrska 64 01601 Kyiv Ukraine

3. Department of Chemical Technology; National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”; Prosp. Peremohy 37 03056 Kyiv Ukraine

4. Institute of Bioorganic Chemistry and Petrochemistry; National Academy of Sciences of Ukraine; Murmanska Street 1 02094 Kyiv Ukraine

5. ChemBioCenter; Taras Shevchenko National University of Kyiv; Volodymyrska 64 01601 Kyiv Ukraine

6. Institute of High Technologies; Taras Shevchenko National University of Kyiv; Hlushkova Avenue, 4G 03022 Kyiv Ukraine

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference74 articles.

1. Scaffold hopping

2. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

3. Conformational Restriction and/or Steric Hindrance in Medicinal Chemistry

4. Lead-Oriented Synthesis: A New Opportunity for Synthetic Chemistry

5. Leitstruktur-orientierte Synthese: eine Alternative für die Synthesechemie

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