Catalytic Friedel‐Crafts Reactions on Saturated Heterocycles and Small Rings for sp 3 ‐sp 2 Coupling of Medicinally Relevant Fragments-Reference-Cited by-同舟云学术

Catalytic Friedel‐Crafts Reactions on Saturated Heterocycles and Small Rings for sp 3 ‐sp 2 Coupling of Medicinally Relevant Fragments

Published:2019-06-12 Issue:31-32 Volume:2019 Page:5385-5395
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur. J. Org. Chem.

Author:

Croft Rosemary A.¹,Dubois Maryne A. J.¹,Boddy Alexander J.¹,Denis Camille¹²,Lazaridou Anna¹,Voisin‐Chiret Anne Sophie²,Bureau Ronan²,Choi Chulho³,Mousseau James J.³,Bull James A.¹^ORCID

Affiliation:

1. Department of Chemistry Imperial College London Molecular Sciences Research Hub, White City Campus Wood Lane London W12 0BZ UK

2. Centre d'Etudes et de Recherche sur le Médicament de Normandie Normandie Univ, UNICAEN, CERMN 14000, Caen France

3. Pfizer Global Research and Development 445 Eastern Point Rd. Groton CT 06340 USA

Funder

Royal Society

Engineering and Physical Sciences Research Council

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ejoc.201900498

Reference105 articles.

1. Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

2. From Oxiranes to Oligomers: Architectures of U.S. FDA Approved Pharmaceuticals Containing Oxygen Heterocycles

3. Rings in Drugs

4. Two‐ and Three‐dimensional Rings in Drugs

5. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

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