Nickel-Catalyzed Ortho C-H Methylation of Aromatic Amides with Di-tert -butyl Peroxide as Methylation Reagent-Reference-Cited by-同舟云学术

Nickel-Catalyzed Ortho C-H Methylation of Aromatic Amides with Di-tert -butyl Peroxide as Methylation Reagent

Published:2019-10-23 Issue:41 Volume:2019 Page:6930-6934
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur. J. Org. Chem.

Author:

Liu Da¹²,Yu Lin¹,Yu Yongqi¹,Xia Zhen¹,Song Zenan¹,Liao Lihong²,Tan Ze¹^ORCID,Chen Xiang¹

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics; College of Chemistry and Chemical Engineering; Hunan University; 410082 Changsha P. R. China

2. College of Chemistry and Chemical Engineering; Kamp Pharmaceuticals CO., LTD.; 415900 Changde P. R. China

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ejoc.201901211/fullpdf

Reference63 articles.

1. Profound Methyl Effects in Drug Discovery and a Call for New CH Methylation Reactions

2. Ausgeprägte Methyleffekte in der Wirkstoff-Forschung und der Bedarf an neuen C-H-Methylierungsreaktionen

3. Methyl Effects on Protein–Ligand Binding

4. Methyl-containing pharmaceuticals: Methylation in drug design

5. The Methylation Effect in Medicinal Chemistry

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