Characterization of preclinicalin vitroandin vivoADME properties and prediction of human PK using a physiologically based pharmacokinetic model for YQA-14, a new dopamine D3receptor antagonist candidate for treatment of drug addiction-Reference-Cited by-同舟云学术

Characterization of preclinicalin vitroandin vivoADME properties and prediction of human PK using a physiologically based pharmacokinetic model for YQA-14, a new dopamine D3receptor antagonist candidate for treatment of drug addiction

Published:2014-04-13 Issue:5 Volume:35 Page:296-307
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm. Drug Dispos.

Author:

Liu Fei¹²,Zhuang Xiaomei¹,Yang Cuiping¹,Li Zheng¹,Xiong Shan¹,Zhang Zhiwei¹,Li Jin¹,Lu Chuang³,Zhang Zhenqing¹

Affiliation:

1. The Key Laboratory of Drug Metabolism and Pharmacokinetics; Beijing Institute of Pharmacology and Toxicology; 27 Taiping Road Beijing 100850 PR China

2. Department of Pharmacy; The First Affiliated Hospital of PLA; 51 Fucheng Road Beijing 10048 PR China

3. Millennium Pharmaceuticals, Inc.; Cambridge Massachusetts USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/bdd.1897/fullpdf

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