Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine-Reference-Cited by-同舟云学术

Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine

Published:2019-06-14 Issue:7 Volume:13 Page:1503-1518
ISSN:1574-7891
Container-title:Molecular Oncology
language:en
Short-container-title:Mol Oncol

Author:

Oo Zay Yar¹²,Proctor Martina¹,Stevenson Alexander J.¹,Nazareth Deborah¹,Fernando Madushan¹,Daignault Sheena M.²,Lanagan Catherine¹,Walpole Sebastian²,Bonazzi Vanessa²³,Škalamera Dubravka¹,Snell Cameron¹⁴,Haass Nikolas K.²,Larsen Jill E.⁵⁶,Gabrielli Brian¹²

Affiliation:

1. Smiling for Smiddy Research Group Translational Research Institute Mater Research Institute‐The University of Queensland Brisbane Australia

2. Translational Research Institute The University of Queensland-Diamantina Institute Brisbane Australia

3. Translational Research Institute Queensland University of Technology Brisbane Australia

4. Mater Pathology Mater Adults HospitalMater Misericordiae Limited South Brisbane Australia

5. QIMR-Berghofer Medical Research Institute The University of Queensland Brisbane Australia

6. School of Medicine The University of Queensland Brisbane Australia

Funder

Cancer Council Queensland

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/1878-0261.12497

Reference46 articles.

1. Successful Long-Term Treatment of Philadelphia Chromosome-Negative Myeloproliferative Neoplasms With Combination of Hydroxyurea and Anagrelide

2. The contribution of dormant origins to genome stability: From cell biology to human genetics

3. cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders

4. HMGB1 loves company

5. Defective Decatenation Checkpoint Function Is a Common Feature of Melanoma

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