Trimethoprim: The overlooked component of trimethoprim-sulfamethoxazole idiosyncratic adverse drug reactions
Author:
Affiliation:
1. Divisions of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Department of Pediatrics, Children's Mercy Hospital; University of Missouri-Kansas City; Kansas City MO USA
Publisher
Wiley
Subject
Pharmacology (medical),Epidemiology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/pds.4574/fullpdf
Reference15 articles.
1. Bioactivation of trimethoprim to protein-reactive metabolites in human liver microsomes;Goldman;Drug Metab Dispos,2016
2. In vitro hepatic oxidative biotransformation of trimethoprim;Goldman;Drug Metab Dispos,2015
3. Urinary biomarkers of trimethoprim bioactivation in vivo following therapeutic dosing in children;Haandel;Chem Res Toxicol,2014
4. Trimethoprim and co-trimoxazole in the treatment of acute urinary tract infections: patient compliance and efficacy;Andrewes;J R Coll Gen Pract,1981
5. Comparison of sulfamethoxazole alone and combined with trimethoprim in urinary tract infections;Bergan;Infection,1979
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