Screening trimethoprim primary metabolites for covalent binding to albumin
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics
Link
http://link.springer.com/content/pdf/10.1007/s00044-020-02570-z.pdf
Reference27 articles.
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3. Cho T, Uetrecht J (2017) How reactive metabolites induce an immune response that sometimes leads to an idiosyncratic drug reaction. Chem Res Toxicol 30:295–314
4. Damsten MC, de Vlieger JS, Niessen WM, Irth H, Vermeulen NP, Commandeur JN (2008) Trimethoprim: novel reactive intermediates and bioactivation pathways by cytochrome p450s. Chem Res Toxicol 21:2181–2187
5. Das G, Bailey MJ, Wickham JE (1988) Toxic epidermal necrolysis and trimethoprim. Br Med J 296:1604–1605
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