Application of a PEG precipitation method for solubility screening: A tool for developing high protein concentration formulations
Author:
Affiliation:
1. Pharmaceutical Research and Development; BioTherapeutics Pharmaceutical Sciences, Pfizer; Andover Massachusetts
Publisher
Wiley
Subject
Molecular Biology,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/pro.2289/fullpdf
Reference17 articles.
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2. The new pre-preclinical paradigm: compound optimization in early and late phase drug discovery;Caldwell;Curr Top Med Chem,2001
3. Determination of the apparent thermodynamic activities of saturated protein solutions;Middaugh;J Biol Chem,1979
4. Fractionation of proteins and viruses with polyethylene glycol;Juckes;Biochim Biophys Acta,1971
5. The precipitation of enzymes from cell extracts of Saccharomyces cerevisiae by polyethylene-glycol;Foster;Biochem Biophys Acta,1973
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