A computational method for predicting the aggregation propensity of IgG1 and IgG4(P) mAbs in common storage buffers
Author:
Affiliation:
1. UCB Pharma, 208 Bath Road, Slough SL1 3WE, UK
Funder
The author(s) reported there is no funding associated with the work featured in this article
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2022.2138092
Reference58 articles.
1. Antibodies to watch in 2020
2. Can the pharmaceutical industry reduce attrition rates?
3. Predicting Antibody Developability Profiles Through Early Stage Discovery Screening
4. Fate of a Stressed Therapeutic Antibody Tracked by Fluorescence Correlation Spectroscopy: Folded Monomers Survive Aggregation
5. Protein aggregation and immunogenicity of biotherapeutics
Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A First Insight into the Developability of an Immunoglobulin G3: A Combined Computational and Experimental Approach;ACS Pharmacology & Translational Science;2024-07-15
2. Prospects for the computational humanization of antibodies and nanobodies;Frontiers in Immunology;2024-05-15
3. A first insight into the developability of an IgG3: A combined computational and experimental approach;2024-05-01
4. Mechanism of Protein Aggregation Inhibition by Arginine: Blockage of Anionic Side Chains Favors Unproductive Encounter Complexes;Journal of the American Chemical Society;2024-03-13
5. Using Passive Microrheology to Measure the Evolution of the Rheological Properties of NIST mAb Formulations during Adsorption to the Air–Water Interface;Langmuir;2024-02-21
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3