Development and validation of an ultra‐high‐performance liquid chromatography–tandem mass spectrometry method to determine the bioavailability of warfarin and its major metabolite 7‐hydroxy warfarin in rats dosed with oral formulations containing different polymorphic forms-Reference-Cited by-同舟云学术

Development and validation of an ultra‐high‐performance liquid chromatography–tandem mass spectrometry method to determine the bioavailability of warfarin and its major metabolite 7‐hydroxy warfarin in rats dosed with oral formulations containing different polymorphic forms

Published:2019-09-09 Issue:12 Volume:33 Page:
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Shakleya Diaa¹^ORCID,Rahman Ziyaur¹²,Faustino Patrick J.¹^ORCID

Affiliation:

1. Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical QualityCenter for Drug Evaluation and Research, Food and Drug Administration Silver Spring MD USA

2. Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science CenterTexas A&M University, College Station TX USA

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bmc.4685

Reference52 articles.

1. Warfarin

2. High-performance liquid-chromatographic determination of warfarin enantiomers in plasma with automated on-line sample enrichment

3. System suitability in bioanalytical LC/MS/MS

4. Brubaker A. N. Tran L. Ntsikoussalabongui B. Killmer J. Humphries D. Bailey D. &Bhattarai D.(2009).Validation of a Chiral LC‐MS/MS Assay for R‐ and S‐Warfarin In Human Plasma to Support Drug‐Drug Interaction Pharmacokinetic Studies. GLRM‐043. American Chemical Society.

5. Quantification of Warfarin in Dried Rat Plasma Spots by High‐Performance Liquid Chromatography with Tandem Mass Spectrometry;Chernonosov A.;Journal of Pharmacy (Cairo),2016

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