NPT1/SLC17A1 Is a Renal Urate Exporter in Humans and Its Common Gain‐of‐Function Variant Decreases the Risk of Renal Underexcretion Gout

Author:

Chiba Toshinori1,Matsuo Hirotaka1,Kawamura Yusuke1,Nagamori Shushi2,Nishiyama Takashi2,Wei Ling2,Nakayama Akiyoshi1,Nakamura Takahiro1,Sakiyama Masayuki1,Takada Tappei3,Taketani Yutaka4,Suma Shino5,Naito Mariko5,Oda Takashi6,Kumagai Hiroo1,Moriyama Yoshinori7,Ichida Kimiyoshi8,Shimizu Toru9,Kanai Yoshikatsu2,Shinomiya Nariyoshi1

Affiliation:

1. National Defense Medical CollegeTokorozawaJapan

2. Osaka UniversityOsakaJapan

3. University of Tokyo Hospital and University of TokyoTokyoJapan

4. University of Tokushima Graduate SchoolTokushimaJapan

5. Nagoya University Graduate School of MedicineNagoyaJapan

6. National Defense Medical College, Tokorozawa, Japan, and Hachioji Medical Center and Tokyo Medical UniversityHachiojiJapan

7. Okayama UniversityOkayamaJapan

8. Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan, and Jikei University School of MedicineTokyoJapan

9. Midorigaoka HospitalOsakaJapan

Funder

Ministry of Education, Culture, Sports, Science, and Technology

the AstraZeneca VRI Research Grant

the Gout Research Foundation of Japan

the Japan Society for the Promotion of Science

the Kawano Masanori Memorial Foundation for Promotion of Pediatrics

the Ministry of Health, Labour and Welfare of Japan

the Takeda Science Foundation

Publisher

Wiley

Subject

Immunology,Rheumatology,Immunology and Allergy

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