Specialist oncological surgery for removal of the ovaries and fallopian tubes in BRCA1 and BRCA2 pathogenic variant carriers may reduce primary peritoneal cancer risk to very low levels

Author:

Crosbie Emma J.12ORCID,Flaum Nicola34,Harkness Elaine F.56,Clayton Richard D.2,Holland Cathrine2,Martin‐Hirsch Pierre17,Wood Nick7,Keating Patrick7,Woodward Emma R.34,Lalloo Fiona4,Donnai Paul2,Edmondson Richard J.12ORCID,Evans D. Gareth34689

Affiliation:

1. Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health University of Manchester, Manchester Academic Health Science Centre Manchester UK

2. Department of Obstetrics and Gynaecology St Mary's Hospital, Manchester University NHS Foundation Trust Manchester UK

3. Division of Evolution and Genomic Sciences School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre Manchester UK

4. Genetic Medicine, Manchester Centre for Genomic Medicine and NW Laboratory Genetics Hub Manchester University Hospitals NHS Foundation Trust Manchester UK

5. Division of Informatics, Imaging and Data Sciences, School of Health Sciences, Faculty of Biology Medicine and Health, University of Manchester Manchester UK

6. Prevention Breast Cancer Centre and Nightingale Breast Screening Centre University Hospital of South Manchester Manchester UK

7. Department of Obstetrics and Gynaecology Royal Preston Hospital, Lancashire Teaching Hospitals NHS Trust Preston UK

8. The Christie NHS Foundation Trust Manchester UK

9. Manchester Breast Centre, Manchester Cancer Research Centre University of Manchester Manchester UK

Funder

Cancer Research UK

National Institute for Health Research

Publisher

Wiley

Subject

Cancer Research,Oncology

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