Decision-making in early clinical drug development
Author:
Affiliation:
1. Early Clinical Development Biometrics; AstraZeneca; Royston UK
2. Clarostat Consulting Ltd.; Alderley Edge UK
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology,Statistics and Probability
Reference8 articles.
1. Trial Watch: Phase II and Phase III attrition rates 2011-2012;Arrowsmith;Nature Reviews Drug Discovery,2013
2. A decade of innovation in pharmaceutical R&D: the Chorus model;Owens;Nature Reviews Drug Discovery,2015
3. Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework;Cook;Nature Reviews Drug Discovery,2014
4. A quantitative process for enhancing end of phase 2 decisions;Sabin;Statistics in Biopharmaceutical Research,2014
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