Overcoming barriers to drug development and enrollment in clinical trials for adolescents and young adults with lymphoma-Reference-Cited by-同舟云学术

Overcoming barriers to drug development and enrollment in clinical trials for adolescents and young adults with lymphoma

Published:2023-09-07 Issue:4 Volume:4 Page:921-926
ISSN:2688-6146
Container-title:eJHaem
language:en
Short-container-title:eJHaem

Author:

Toner Keri¹^ORCID,Allen Carl E.²,Jain Shweta³,Kahl Brad⁴,Leonard John⁵,Wasserstrom Heather⁶,Friedberg Jonathan W.⁷,Seibel Nita L.⁸,Kelly Kara⁹

Affiliation:

1. Center for Cancer and Blood Disorders Children's National Hospital Washington District of Columbia USA

2. Baylor College of Medicine Texas Children's Hospital Houston Texas USA

3. Clinical Development Seagen Inc. Bothell Washington USA

4. Department of Medicine Division of Oncology Washington University in St. Louis School of Medicine St. Louis Missouri USA

5. Weill Department of Medicine Division of Hematology and Medical Oncology Weill Cornell Medicine New York New York USA

6. Clinical Development Team Pediatrics Hematology and Cellular Therapy at Bristol Myers Squibb New York New York USA

7. Wilmot Cancer Institute University of Rochester Rochester New York USA

8. Division of Cancer Treatment and Diagnosis National Cancer Institute National Institutes of Health Bethesda Maryland USA

9. Roswell Park Comprehensive Cancer Center University at Buffalo Jacobs School of Medicine and Biomedical Sciences Buffalo New York USA

Abstract

AbstractLymphoma is one of the most common cancers in adolescents and young adults, but historically, this population has had lower clinical trial enrollment and improvements in overall survival as compared to other age populations. There are multiple challenges that are unique to this population that have affected drug development and clinical trial enrollment. Our panel of experts have identified barriers, and in this review, we discuss current methods to address these barriers as well as potential solutions moving forward.

Publisher

Wiley

Subject

General Earth and Planetary Sciences

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jha2.787

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