GABAergic modulation of secondary hyperalgesia: A randomized controlled 4‐way crossover trial with the α2‐subunit preferring GABA positive allosteric modulator, N ‐desmethyl‐clobazam in healthy volunteers

Author:

Matthey Alain1,Daali Youssef12,Curtin François12,Poncet Antoine3,Desmeules Jules12,Besson Marie12

Affiliation:

1. Division of Clinical Pharmacology and Toxicology Multidisciplinary Pain Center Geneva University Hospitals Geneva Switzerland

2. Faculty of Medicine Geneva University Geneva Switzerland

3. Division of Clinical Epidemiology Geneva University Hospitals Geneva Switzerland

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine

Reference42 articles.

1. Pharmacotherapy of neuropathic pain

2. EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision

3. Opioids for the Treatment of Chronic Pain

4. The Molecular Architecture of GABAA Receptors

5. International Union of Pharmacology. XV. Subtypes of gamma‐aminobutyric acidA receptors: Classification on the basis of subunit structure and receptor function;Barnard E. A.;Pharmacological Reviews,1998

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