The orally bioavailable imidazodiazepine, KRM-II-81, is a novel potentiator of α2/3-containing GABAA receptors with analgesic efficacy-Reference-Cited by-同舟云学术

The orally bioavailable imidazodiazepine, KRM-II-81, is a novel potentiator of α2/3-containing GABAA receptors with analgesic efficacy

Published:2022 Issue: Volume: Page:117-127
ISSN:
Container-title:The Neurobiology, Physiology, and Psychology of Pain
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Author:

Cerne Rok,Smith Jodi L.,Fisher Janet L.,Golani Lalit K.,Knutson Daniel E.,Cook James M.,Witkin Jeffrey M.

Publisher

Elsevier

Reference78 articles.

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5. The α2,3-selective potentiators of GABAA receptors, KRM-II-81 and MP-III-80, produce anxiolytic-like effects and block chemotherapy-induced hyperalgesia in mice without tolerance development;Biggerstaff;Pharmacology, Biochemistry and Behavior,2020

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1. Structural Analogs of the GABAkine KRM-II-81 Are Orally Bioavailable Anticonvulsants without Sedation;Journal of Pharmacology and Experimental Therapeutics;2023-02-06

2. Hydrochloride Salt of the GABAkine KRM-II-81;ACS Omega;2022-07-27