Diethylnitrosamine genotoxicity evaluated in sprague dawley rats usingPig-amutation and reticulocyte micronucleus assays

Author:

Avlasevich Svetlana L.1,Phonethepswath Souk1,Labash Carson1,Carlson Kristine1,Torous Dorothea K.1,Cottom John1,Bemis Jeffrey C.1,MacGregor James T.2,Dertinger Stephen D.1

Affiliation:

1. Litron Laboratories; Rochester New York

2. Toxicology Consulting Services; Bonita Springs Florida

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Genetics(clinical),Epidemiology

Reference24 articles.

1. Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individuals;Araten;Proc Natl Acad Sci USA,1999

2. Report on Stage III Pig-a mutation assays using benzo[a]pyrene;Bhalli;Environ Mol Mutagen,2011

3. In vivo mutation assay based on the endogenous Pig-a locus;Bryce;Environ Mol Mutagen,2008

4. Report on Stage III Pig-a mutation assays using N-ethyl-N-nitrosourea-Comparison with other in vivo genotoxicity endpoints;Cammerer;Environ Mol Mutagen,2011

5. Glycophosphatidylinositol-anchored protein deficiency as a marker of mutator phenotypes in cancer;Chen;Cancer Res,2001

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