Inhibition of the PLK1‐Coupled Cell Cycle Machinery Overcomes Resistance to Oxaliplatin in Colorectal Cancer

Author:

Yu Zhaoliang1,Deng Peng2,Chen Yufeng1,Liu Shini2,Chen Jinghong2,Yang Zihuan3,Chen Jianfeng2,Fan Xinjuan4,Wang Peili2,Cai Zerong1,Wang Yali2,Hu Peishan3,Lin Dezheng5,Xiao Rong6,Zou Yifeng1,Huang Yan4,Yu Qiang78,Lan Ping13,Tan Jing29ORCID,Wu Xiaojian13

Affiliation:

1. Department of Colorectal Surgery The Sixth Affiliated Hospital Sun Yat‐sen University Guangzhou Guangdong 510655 P. R. China

2. Sun Yat‐sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou Guangdong 510060 P. R. China

3. Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases Guangdong Institute of Gastroenterology The Sixth Affiliated Hospital Sun Yat‐sen University Guangzhou Guangdong 510655 P. R. China

4. Department of Pathology The Sixth Affiliated Hospital Sun Yat‐sen University Guangzhou Guangdong 510060 P. R. China

5. Department of Endoscopic Surgery The Sixth Affiliated Hospital Sun Yat‐sen University Guangzhou Guangdong 510060 P. R. China

6. Department of Biomedical Sciences City University of Hong Kong Hong Kong SAR 999077 China

7. Cancer and Stem Cell Biology Program Duke‐NUS Medical School Singapore 169857 Singapore

8. Genome Institute of Singapore A*STAR Singapore 138672 Singapore

9. Affiliated Cancer Hospital and Institute of Guangzhou Medical University Guangzhou Guangdong 510095 P. R. China

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Guangdong Province

Medical Science and Technology Foundation of Guangdong Province

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

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