1. Department of Pharmacy Xiangya Hospital Central South University Changsha Hunan 410008 P. R. China
2. National Clinical Research Center for Geriatric Disorders Xiangya Hospital Central South University Changsha Hunan 410008 P. R. China
3. Xiangya School of Pharmaceutical Sciences Central South University Changsha Hunan 410078 P. R. China
4. Hunan Provincial Key Laboratory of Cardiovascular Research Xiangya School of Pharmaceutical Sciences Central South University Changsha Hunan 410078 P. R. China