Recent Progress in Photothermal, Photodynamic and Sonodynamic Cancer Therapy: Through the cGAS-STING Pathway to Efficacy-Enhancing Strategies-Reference-Cited by-同舟云学术

Recent Progress in Photothermal, Photodynamic and Sonodynamic Cancer Therapy: Through the cGAS-STING Pathway to Efficacy-Enhancing Strategies

Published:2024-08-05 Issue:15 Volume:29 Page:3704
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Fang Kelan¹²,Zhang Huiling¹³,Kong Qinghong¹²,Ma Yunli¹,Xiong Tianchan¹²,Qin Tengyao¹²,Li Sanhua¹²,Zhu Xinting¹²^ORCID

Affiliation:

1. Guizhou Provincial College-Based Key Lab for Tumor Prevention and Treatment with Distinctive Medicines, Zunyi Medical University, Zunyi 563000, China

2. College of Basic Medicine, Zunyi Medical University, Zunyi 563000, China

3. Department of Medicine and Pharmacy, Shizhen College of Guizhou University of Traditional Chinese Medicine, Guiyang 550000, China

Abstract

Photothermal, photodynamic and sonodynamic cancer therapies offer opportunities for precise tumor ablation and reduce side effects. The cyclic guanylate adenylate synthase-stimulator of interferon genes (cGAS-STING) pathway has been considered a potential target to stimulate the immune system in patients and achieve a sustained immune response. Combining photothermal, photodynamic and sonodynamic therapies with cGAS-STING agonists represents a newly developed cancer treatment demonstrating noticeable innovation in its impact on the immune system. Recent reviews have concentrated on diverse materials and their function in cancer therapy. In this review, we focus on the molecular mechanism of photothermal, photodynamic and sonodynamic cancer therapies and the connected role of cGAS-STING agonists in treating cancer.

Funder

National Natural Science Foundation of China

Technology Foundation of Guizhou Province

Project of Education Department of Guizhou Province

Innovation and Entrepreneurship Project for College Students of ZMU

Publisher

MDPI AG

Link

https://www.mdpi.com/1420-3049/29/15/3704/pdf

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