Nurr1 Modulation Mediates Neuroprotective Effects of Statins-Reference-Cited by-同舟云学术

Nurr1 Modulation Mediates Neuroprotective Effects of Statins

Published:2022-04-30 Issue:18 Volume:9 Page:2104640
ISSN:2198-3844
Container-title:Advanced Science
language:en
Short-container-title:Advanced Science

Author:

Willems Sabine¹^ORCID,Marschner Julian A.²,Kilu Whitney¹,Faudone Giuseppe¹,Busch Romy²,Duensing‐Kropp Silke²,Heering Jan³,Merk Daniel¹²^ORCID

Affiliation:

1. Institute of Pharmaceutical Chemistry Goethe University Frankfurt Max‐von‐Laue‐Str. 9 Frankfurt 60438 Germany

2. Department of Pharmacy Ludwig‐Maximilians‐Universität München Butenandtstr. 5‐13 Munich 81377 Germany

3. Fraunhofer Institute for Translational Medicine and Pharmacology ITMP Theodor‐Stern‐Kai 7 Frankfurt 60596 Germany

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/advs.202104640

Reference72 articles.

1. Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors

2. NURR1 in Parkinson disease—from pathogenesis to therapeutic potential

3. Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s disease

4. Nurr1 overexpression exerts neuroprotective and anti-inflammatory roles via down-regulating CCL2 expression in both in vivo and in vitro Parkinson's disease models

5. Nurr1 reduction influences the onset of chronic EAE in mice

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