1H-MRS processing parameters affect metabolite quantification: The urgent need for uniform and transparent standardization

Author:

Bhogal Alex A.1ORCID,Schür Remmelt R.2,Houtepen Lotte C.2,van de Bank Bart3,Boer Vincent O.4,Marsman Anouk4,Barker Peter B.5,Scheenen Tom W.J.3,Wijnen Jannie P.1,Vinkers Christiaan H.2,Klomp Dennis W.J.1

Affiliation:

1. Radiology Department; University Medical Center Utrecht; Utrecht the Netherlands

2. Psychiatry Department; University Medical Center Utrecht; Utrecht the Netherlands

3. Department of Radiology and Nuclear Medicine; Radboud University Medical Center; Nijmegen the Netherlands

4. Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research; Copenhagen University Hospital Hvidovre; Hvidovre Denmark

5. Department of Radiology and Radiological Science - Neuroradiology; Johns Hopkins University School of Medicine; Baltimore MD USA

Publisher

Wiley

Subject

Spectroscopy,Radiology Nuclear Medicine and imaging,Molecular Medicine

Reference34 articles.

1. Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites;Frahm;Magn Reson Med,1989

2. Absolute concentrations of metabolites in the adult human brain in vivo: quantification of localized proton MR spectra;Michaelis;Radiology,1993

3. Luyten P van Ryen P Tulleken C Den Hollander J Metabolite mapping using 1 H NMR spectroscopic imaging in patients with cerebrovascular disease 1989 452 258

4. 3D phase encoding 1H spectroscopic imaging of human brain;Duijn;Magn Reson Imaging,1992

5. H MR spectroscopy of the brain: absolute quantification of metabolites;Jansen;Radiology,2006

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