Improving Catalytic Activity and Reversing Enantio‐Specificity of ω‐Transaminase by Semi‐Rational Engineering en Route to Chiral Bulky β‐Amino Esters-Reference-Cited by-同舟云学术

Improving Catalytic Activity and Reversing Enantio‐Specificity of ω‐Transaminase by Semi‐Rational Engineering en Route to Chiral Bulky β‐Amino Esters

Published:2021-06-17 Issue:15 Volume:13 Page:3396-3400
ISSN:1867-3880
Container-title:ChemCatChem
language:en
Short-container-title:ChemCatChem

Author:

Wang Yingang¹²,Feng Jinhui¹²,Dong Wenyue²,Chen Xi¹²,Yao Peiyuan¹²,Wu Qiaqing¹²^ORCID,Zhu Dunming¹²

Affiliation:

1. University of Chinese Academy of Sciences No.19(A) Yuquan Road Shijingshan District, Beijing 100049 P.R. China

2. National Technology Innovation Center for Synthetic Biology National Engineering Laboratory for Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology Tianjin Institute of Industrial Biotechnology Chinese Academy of Sciences 32 Xi Qi Dao Tianjin Airport Economic Area, Tianjin 300308 P.R. China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cctc.202100503

Reference82 articles.

2. Discovery, Engineering, and Synthetic Application of Transaminase Biocatalysts

3. High-Yield Biocatalytic Amination Reactions in Organic Synthesis

4. Application of ω-Transaminases in the Pharmaceutical Industry

5. Transaminase biocatalysis: optimization and application

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