Effective temperature shift strategy development and scale confirmation for simultaneous optimization of protein productivity and quality in Chinese hamster ovary cells
Author:
Affiliation:
1. Global Product Development and SupplyBristol‐Myers Squibb Company Devens Massachusetts
Funder
Bristol-Myers Squibb
Publisher
Wiley
Subject
Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.2959
Reference50 articles.
1. CHO Quasispecies—Implications for Manufacturing Processes
2. The choice of mammalian cell host and possibilities for glycosylation engineering
3. CHO cells in biotechnology for production of recombinant proteins: current state and further potential
4. Mammalian cell protein expression for biopharmaceutical production
5. Transcriptome and proteome analysis of Chinese hamster ovary cells under low temperature and butyrate treatment
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