Data-driven parameterization and development of mechanistic cell cultivation models in monoclonal antibody production processes: Shifts in cell metabolic behavior

Author:

Okamura Kozue,Oishi KotaORCID,Badr SaraORCID,Yamada Akira,Sugiyama Hirokazu

Funder

Japan Agency for Medical Research and Development

Publisher

Elsevier BV

Reference46 articles.

1. Parallel labeling experiments with [1,2-13C]glucose and [U-13C]glutamine provide new insights into CHO cell metabolism;Ahn;Metab. Eng.,2013

2. Hybrid modelling and data-driven parameterization of monoclonal antibody cultivation processes: shifts in cell metabolic behavior;Badr;Comput. Aid. Chemic. Eng.,2023

3. Integrated design of biopharmaceutical manufacturing processes: operation modes and process configurations for monoclonal antibody production;Badr;Comput. Chemic. Eng.,2021

4. A PSE perspective for the efficient production of monoclonal antibodies: integration of process, cell, and product design aspects;Badr;Curr. Opin. Chem. Eng.,2020

5. The less the better: how suppressed base addition boosts production of monoclonal antibodies with Chinese hamster ovary cells;Becker;Front. Bioeng. Biotechnol.,2019

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3