Metabolic profiling of a novel antithrombotic compound, S002-333 and enantiomers: metabolic stability, species comparison andin vitro-in vivoextrapolation
Author:
Affiliation:
1. Pharmacokinetics and Metabolism Division; CSIR - Central Drug Research Institute; Lucknow 226031 India
2. Medicinal and Processing Chemistry Division; CSIR - Central Drug Research Institute; Lucknow 226031 India
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine
Reference35 articles.
1. Epidemiology and risk factors for venous thrombosis;Cushman;Semin Hematol,2007
2. The role of collagen in thrombosis and hemostasis;Farndale;J Thromb Haemost,2004
3. GPVI and alpha2beta1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow;Sarratt;Blood,2005
4. Platelet adhesion to cyanogen-bromide fragments of collagen alpha 1(I) under flow conditions;Saelman;Blood,1993
5. Platelet collagen receptors, signaling and antagonism: emerging approaches for the prevention of intravascular thrombosis;Surin;Thromb Res,2008
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