Evaluation of oral pharmacokinetics, in vitro metabolism, blood partitioning and plasma protein binding of novel antidiabetic agent, S009-0629 in rats

Author:

Valicherla Guru Raghavendra12,Italiya Kishan Shamjibhai3,Gupta Chandra Prakash4,Mishra Shachi4,Riyazuddin Mohammed1,Syed Anees Ahmed1,Singh Sandeep Kumar1,Shahi Sudhir1,Taneja Gaurav4,Wahajuddin Mohammad12,Goel Atul24,Gayen Jiaur Rahaman12ORCID

Affiliation:

1. Pharmaceutics and Pharmacokinetics Division; CSIR-Central Drug Research Institute (CDRI); Lucknow India

2. Academy of Scientific and Innovative Research (AcSIR); New Delhi India

3. Department of Pharmaceutics; National Institute of Pharmaceutical Education and Research; Raebareli India

4. Medicinal and Process Chemistry Division; CSIR-Central Drug Research Institute (CDRI); Lucknow India

Publisher

Wiley

Subject

Drug Discovery

Reference20 articles.

1. Physiological parameters in laboratory animals and humans;Davies;Pharmaceutical Research,1993

2. Goel , A. Taneja , G. Rahuja , N. Rawat , A. K. Jaiswal , N. Tamrakar , A. K. Srivastava , A. K. 2013 Patent US2015/000/5357A1

3. In vitro metabolism of the alkaloid piplartine by rat liver microsomes;Marques;Journal of Pharmaceutical and Biomedical Analysis,2014

4. In Vitro and In Vivo pharmacokinetic studies of bulaquine (analogue of primaquine), a novel antirelapse antimalarial, in rat, rabbit and monkey-highlighting species similarities and differences;Mehrotra;Biopharmaceutics & Drug Disposition,2007

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