Determination of permeability, plasma protein binding, blood partitioning, pharmacokinetics and tissue distribution of Withanolide A in rats: A neuroprotective steroidal lactone-Reference-Cited by-同舟云学术

Determination of permeability, plasma protein binding, blood partitioning, pharmacokinetics and tissue distribution of Withanolide A in rats: A neuroprotective steroidal lactone

Published:2018-10-04 Issue:7 Volume:79 Page:339-351
ISSN:0272-4391
Container-title:Drug Development Research
language:en
Short-container-title:Drug Dev Res

Author:

Singh Sandeep K.¹²,Valicherla Guru R.¹²,Joshi Pankaj¹,Shahi Sudhir¹,Syed Anees A.¹,Gupta Anand P.¹,Hossain Zakir¹,Italiya Kishan³,Makadia Vishal³,Singh Shio K.¹,Wahajuddin Mohammad¹²,Gayen Jiaur R.¹²^ORCID

Affiliation:

1. Division of Pharmaceutics & Pharmacokinetics; CSIR-Central Drug Research Institute; Lucknow Uttar Pradesh India

2. Academy of Scientific and Innovative Research (AcSIR); New Delhi India

3. Department of Pharmaceutics; National Institute of Pharmaceutical Education and Research; Raibareli Uttar Pradesh India

Funder

Department of Biotechnology

University Grants Commission

Council of Scientific and Industrial Research

Publisher

Wiley

Subject

Drug Discovery

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ddr.21463/fullpdf

Reference48 articles.

1. Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation;Agarwal;Journal of Ethnopharmacology,1999

2. Neuro-protective potential of a vesicular system of a standardized extract of a new chemotype of Withania somnifera Dunal (NMITLI118RT+) against cerebral stroke in rats;Ahmad;Drug Delivery,2016

3. Withanolide a offers neuroprotection, ameliorates stress resistance and prolongs the life expectancy of Caenorhabditis elegans;Akhoon;Experimental Gerontology,2016

4. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root;Andallu;Indian Journal of Experimental Biology,2000

5. Antistressor effect of Withania somnifera;Archana;Journal of Ethnopharmacology,1998

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